I'm officially in heaven! I've been having serious repetitive strain injuries in my wrist and thumb, exacerbated by having my wrist rest on the desktop when I used my mouse (ditto using a keyboard that had no latches to raise the backside up an inch or so). I found a used but like-new keyboard I'd saved from an old computer that has the latches, and it's made a big difference. Then, Lilla's brother Iain suggested getting a "vertical" mouse. Say what? Well, I took a look at Amazon and the rest is history. Very comfortable and intuitive to use. Love it! On the right side are the right- and left-click buttons and scroll bar; the left side (right) has a bunch of functions I'll probably never use.